The nature of consciousness, once the exclusive realm of philosophers, has been, very gradually penetrated by neuroscientists, biologists, and physicists. Consciousness has always been defined as the Hard Problem in all these subjects.
With the emergence of unprecedented devices and the development of multidisciplinary experiments in different research fields, more details of this hard problem have been revealed, especially in quantum mechanics and neuroscientific fields. Quantum computers are considered the brightest new star in the quantum field and increasingly fascinate quantum physicists and information technology specialists. Advances in new materials and cryogenic physics have led to remarkable breakthroughs in quantum computing in recent years. Because quantum mechanics deals with the tiniest constituents of the material world, it seems capable of elucidating numerous unsolved and tough problems. Quantum theory, a branch from the finer scale of consciousness, has been accompanied by numerous controversies since its inception, but abundant proof demonstrated that this theoretical framework is capable of explaining the majority of consciousness problems that traditional neuroscience could not, especially the orchestrated objective reduction (Orch-OR) theory introduced by Penrose and Hameroff.
It was widely accepted that most neuronal communication and information transmission initially occurred on receptors and ligands (especially among synapses in the central nervous system) on the cell membrane, followed by second messengers that broadcast or transfer the information to various parts of the interior cell. Almost all basic studies in neurobiology converge on the various receptors, ligands and signaling pathways. However, are we 100% certain about this prerequisite basis of neuroscience? Rather than the conventional receptors and ligands of the membrane, the principal cellular components of the Orch-OR theory are microtubules that are mostly considered pivotal structures for material transportation, cell movement, mitosis and establishment and maintenance of cell form and function.
To date, this theory has remained one of the most acceptable and continuous theories that covers in detail quantum physics, quantum gravity, quantum information theory, molecular biology, neuroscience, cognitive science, philosophy, and anesthesiology. Additionally, this theory was known to neurobiologists who were interested in the “Hard Problem” as well as physicists and philosophers.
Under the background of rapid development of world computer technology, Hameroff likened the flow of information in the brain to computers in which microtubules were to the brain what transistors were to the computer (40-43). Inspired by this fantastic analogy and Gödel’s incompleteness theorems, in The Emperor’s New Mind (44) published in 1989, Roger Penrose first attached the quantum effect in human cognition. For example, he considered whether consciousness can affect quantum mechanics or vice versa and that quantum mechanics itself might be included in consciousness. Penrose suggested that the “objective collapse”, that is, the collapse and superposition of quantum interference, is a real physical process, similar to the bursting of bubbles (44). Furthermore, consciousness was the product of quantum space-time structure (Figure 2), which was inextricably related to the universe, and the theory describing the relationship between consciousness and the universe was the Orch-OR theory (44). These quantum theories facilitated the emergence of later biological hypotheses of consciousness based on quantum mechanics.